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Treatment with statins compromised gatekeeper proteins called ryanodine receptors, which control calcium release from storage compartments in muscle cells, leading to spontaneous and irregular calcium leaks that could trigger signals promoting cell death. simvastatin to 23% for subjects on pravastatin see Table E2.
There was evidence that statins with increased hydrophilicity as measured by ... Nelfinavir boceprevir, telaprevir, erythromycin, clarithromycin, telithromycin, nefazodone, and medicinal products containing cobicistat is contraindicated see sections 4. and 4.
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